The Northern Quarters always a winner, especially Bluu, Walrus and TV 21s had some good nights in Mint Lounge to on Oldham Street as well. If you fancy pastures new considering that the NQ gets sarged pretty hard on a regular basis. Didsbury Village, West Didsbury (especially for 9s/10s) and Chorlton are a good and more genteel and relaxed alternative to the city centre.